tag:blogger.com,1999:blog-14162253.post859560796868396794..comments2024-03-17T10:49:06.420-06:00Comments on Wash Park Prophet: Schizophrenia genes may make you a better dateAndrew Oh-Willekehttp://www.blogger.com/profile/02537151821869153861noreply@blogger.comBlogger6125tag:blogger.com,1999:blog-14162253.post-10017506468871532462014-11-27T00:02:14.270-07:002014-11-27T00:02:14.270-07:00Alex you still have schizophrenia, taking vitamin ...Alex you still have schizophrenia, taking vitamin b-3 for a month did not cure it lol... that was a delusional comment. i do them all the timeAnonymousnoreply@blogger.comtag:blogger.com,1999:blog-14162253.post-31841139095704675942014-01-02T01:31:48.824-07:002014-01-02T01:31:48.824-07:00Sorry, Alex but what you say doesn't make much...Sorry, Alex but what you say doesn't make much sense. Niacin is not the typical vitamin only found in fish but rather its main dietary source may be liver, although there's a variety of them, including peanut butter and common meats like chicken or beef - fish may be one source but not a necessary one. Where fish may be important is for vitamin D generation, especially among people with darker skin colors living in high latitudes: vitamin D is either synthesized in the skin by exposure to sunlight, fish or pharmaceutical supplements. Vitamin D is the most critical cause of visible evolutive differentiation in humans and that's because it is fundamental in early brain development (fetal and infancy), as well as affecting bone formation. And that's precisely because fish was not always available as part of the diet (otherwise depigmentation would not have been as necessary). I'd strongly recommend vit. D supplements (or a fish-rich diet) for mothers and children (and to lesser extent other adults) of dark pigmentation living far away from the tropics. Its developmental deficiency can cause mild to severe mental problems, which AFAIK are not reversible. <br /><br />I don't mean to question the veracity of what you say but the logic implicit in it. Vitamin B3 deficiency is well known medically and causes pellagra, which affects the skin and the brain but causing dementia rather than schizophrenia. Anyhow in a meat-rich diet, vitamin B3 should be plentiful, even maybe excessive: you get 5-6 mg per 100 g of beef or slightly more from chicken and the recommended dose is of around 14-18 mg (= three small meat rations), depending on age or gender. Cereals, legumes, nuts or even green vegetables like broccoli also provide niacin in variable doses. Majuhttps://www.blogger.com/profile/12369840391933337204noreply@blogger.comtag:blogger.com,1999:blog-14162253.post-11409490116029236512014-01-01T23:59:05.347-07:002014-01-01T23:59:05.347-07:00All of these theories are valid, but the missing h...All of these theories are valid, but the missing hole in all of this is Vitamin B3. Also known as Niacin. A deficiency is the cause of schizophrenia, bipolar disorder, depression, and anxiety. Our ancestors ate plenty of fish, which contain high amounts of niacin, so that they did not have this deficiency. I developed schizophrenia at 19 years old and cured it by supplementing with niacin every day for a month.Anonymoushttps://www.blogger.com/profile/06190768921449544231noreply@blogger.comtag:blogger.com,1999:blog-14162253.post-61441590469793916802011-01-05T17:34:46.115-07:002011-01-05T17:34:46.115-07:00I'm not talking mothers but children. The trau...I'm not talking mothers but children. The traumas of medicalized birth may and should cause epigenetic modifications which may favor schizophrenia and other mental disorders later in life. <br /><br />I do not mean to disregard genetic factors, which do exist, but generally schizophrenia sets on in early adulthood. It's not any old-age disease like Parkinson or most cancers, which have a low fitness cost: it is a highly disabling illness that affects specially young adults (all people I know developed it in their teens or twenties). So your claim that it may provide with any reproductive advantage seems most odd, unless it is in their relatives with unexpressed genes. <br /><br />I'd rather tend to see it as a genetically influenced disorder with low prevalence in normal conditions (i.e. Paleolithic or even Neolithic ones) aggravated by modern maternity practices, which trigger the disease in people who would have otherwise been "normal" (more or less).<br /><br />Thanks for the clarification on Romans, I was not sure where I had read the youth mortality explanation.Majuhttps://www.blogger.com/profile/12369840391933337204noreply@blogger.comtag:blogger.com,1999:blog-14162253.post-59398450878206548912011-01-05T12:40:42.757-07:002011-01-05T12:40:42.757-07:00My source for the life expectency of Romans is fro...My source for the life expectency of Romans is from the link in the my first recent post on that subject, which finds something close to a consensus in the literature on that point drawing on multiple lines of evidence that all reach the same conclusion. In addition to very high infant mortality, TB and general communicable illness death associated with malnutrition were important killers of young adults. Romans who survived their twenties often did live to near modern ages as I noted in the first post on the subject. Most societies that are less medically modern, and particularly those with high rates of infant mortality, also have very high rates of maternal mortality in childbirth. A typical pre-modern society has an excess of older men relative to older women in times of peace (warfare can, of course, shift the balance the other way). Colonial America, for example, had far more widowers than widows (exactly the reverse of modern age/gender balances). The upper crust in Rome did live longer (as the source I reference and quote included in the post note), but even in the most affluent Roman communities had life expectencies of only about 40 years old. I've previously cited in a post the example of George Washington's extended family as an example of just how common early deaths were, even among the affluent in societies that lack modern medical science.<br /><br />The onset of schizophrenia in mothers often does come close in time to child bearing, as I have noted in a previous post, but given the characteristic time of schizophrenia onset in women in any case (the most plausible explanation of which neurobiologically is unrelated to child bearing) makes this more likely to be a largely coincidental factor, and the consistency of schizophrenia rates in places with very different childbearing practices and over time periods when childbearing practies have changed a great deal, undermines this hypothesis. The extremely high levels of hereditary influence in schizophrenia incidence also contradicts child birthing practices as an important factor for either mothers or their children. Schizophrenia rates are profoundly lower in people with no family history of schizophrenia than they are with people who do have that family history, even controlling for birthing method differences. A trend towards parenting by older fathers provides a more empirically supported basis for any uptake in schizophrenia rates that has been observed.Andrew Oh-Willekehttps://www.blogger.com/profile/02537151821869153861noreply@blogger.comtag:blogger.com,1999:blog-14162253.post-64794869213478531062011-01-05T12:23:18.469-07:002011-01-05T12:23:18.469-07:00I've read twice recently in your blog that lif...I've read twice recently in your blog that life expectancy among Romans was 20-30 years. I think you are being mislead by high child mortality and maybe also high slave mortality (probably the average life expectancy of slaves was about 20 years). <br /><br />I am quite sure of having read elsewhere that these figures are highly distorted by elevated child mortality and that people who reached adolescence could expect to live almost as much as we do (maybe 60 years on average). <br /><br />As for schizophrenia, I am persuaded that, regardless of genetic susceptibility factors, it is being dramatically increased by modern medicalization of birthgiving, specially anti-natural practices such as forcing women to give birth in most unnatural positions (advantageous for the surgeon), abuse of drugs and cesareans in birthgiving and, very specially, separation of mother and child for hours after birth, all of which is very traumatic for children and may severely compromise the natural development of the mind.Majuhttps://www.blogger.com/profile/12369840391933337204noreply@blogger.com